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FAQ | Inflammation & the Joint

Live long enough and you can pretty much count on developing arthritis: a touch of osteoarthritis, at the very least.

Inflammation & the Joint

Inflammation is involved in many forms of arthritis. It is the body's natural response to injury. The warning signs that inflammation presents are redness, swelling, heat and pain. These are the same kinds of reaction the body has to a sliver in the hand, for example. When a joint becomes inflamed, it may get any or all of these symptoms. This can prevent the normal use of the joint and therefore it can cause the loss of function of that joint.

There are more than 100 joints connecting the body's 206 bones. Most of the major bone connections in the body are joints designed to allow a broad range of motion. There are different kinds for different functions: ball-and-socket (hips and shoulders), saddle joints (which connect thumb to hand) hinge joints (fingers and knees) or pivot joints (wrists). Tied together by ligaments, the bones of joints are capped with a smooth substance called cartilage. This tough elastic material acts as a shock absorber and allows the bone ends to glide smoothly across each other. If the cartilage is destroyed (as in osteoarthritis), the bones of a joint can grind against each other causing pain, loss of mobility, deformity and dysfunction.

Between the bones is a joint cavity, which gives the bones room to move. The joint space between two bones is enclosed by a capsule that's flexible, yet strong enough to protect the joint against dislocation. The inner lining of this capsule, the synovium, produces a thick fluid that lubricates and nourishes the joint. In many forms of arthritis, the synovium becomes inflamed and thickened, producing extra fluid which contains inflammatory cells. The inflamed synovium and fluid can damage the cartilage and underlying bone.

 

 

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