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Healthcare
Home/Healthcare/SARS

GENERAL INFORMATION
8 May 2003

WHAT IS SARS?
SARS, or Severe Acute Respiratory Syndrome, is a new type of atypical pneumonia that affects the lungs. The World Health Organization (WHO) and the United States Center for Disease Control (CDC) have pointed to a previously unknown member of the family of coronaviruses as the cause for SARS.

WHAT ARE THE TERMINOLOGIES I NEED TO KNOW? (Based on WHO - May 1, 2003)

Suspect Case
1. A person presenting after 1 November 20021 with history of:

- high fever (>38oC)
AND
- cough or breathing difficulty
AND one or more of the following exposures during the 10 days prior to onset of symptoms:

- close contact2 with a person who is a suspect or probable case of SARS;

- history of travel, to an area with recent local transmission of SARS

- residing in an area with recent local transmission of SARS

2. A person with an unexplained acute respiratory illness resulting in death after 1 November 2002,1 but on whom no autopsy has been performedAND one or more of the following exposures during 10 days prior to onset of
symptoms:

- close contact2 with a person who is a suspect or probable case of SARS;

- history of travel, to an area with recent local transmission of SARS

- residing in an area with recent local transmission of SARS

Probable case
1. A suspect case with radiographic evidence of infiltrates consistent with
pneumonia or respiratory distress syndrome (RDS) on chest X-ray (CXR).

2. A suspect case of SARS that is positive for SARS coronavirus by one or
more assays.

3. A suspect case with autopsy findings consistent with the pathology of RDS without an identifiable cause.

Exclusion Criteria
A case should be excluded if an alternative diagnosis can fully explain their illness.

Reclassification of cases
As SARS is currently a diagnosis of exclusion, the status of a reported case may change over time. A patient should always be managed as clinically appropriate, regardless of their case status.

- A case initially classified as suspect or probable, for whom an alternative diagnosis can fully explain the illness, should be discarded after
carefully considering the possibility of co-infection.

- A suspect case who, after investigation, fulfills the probable case definition should be classified as “probable”.

- A suspect case with a normal CXR should be treated, as deemed appropriate, and monitored for 7 days. Those cases in whom recovery is inadequate should be re-evaluated by CXR.

- Those suspect cases in whom recovery is adequate but whose illness cannot be fully explained by an alternative diagnosis should remain as “suspect”.

- A suspect case who dies, on whom no autopsy is conducted, should remain classified as “suspect”. However, if this case is identified as being part of a chain transmission of SARS, the case should be reclassified as
“probable”.

- If an autopsy is conducted and no pathological evidence of RDS is found, the case should be “discarded”.

1. The surveillance period begins on November 2002 to capture cases of a typical pneumonia in China now recognized as SARS. International transmission of SARS was first reported in March 2003 for cases with onset in February 2003.

2. Close contact: having cared for, lived with, or had direct contact with respiratory secretions or body fluids of a suspect or probable case of SARS.

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